1. (Verb): Abandon hope; give up hope; lose heart
2. (Noun): A state in which all hope is lost or absent
1. Don't despair--help is on the way!
2. In the depths of despair
3. They were rescued from despair at the last minute
4. Courage born of desperation
1. Desperation
2. Despair
1. Hope
1. Despond
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